Increased body fluid purine levels during hypotensive events

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Increased body fluid purine levels during hypotensive events. Evidence for ATP degradation.

Tissue ischemia leads to adenosine triphosphate (ATP) breakdown with elevation of body fluid ATP metabolites. This study tests the hypothesis that there is a direct relationship between periods of hypotension and body fluid uric acid and oxypurine levels in 19 prospectively studied patients. Significant elevations in urine oxypurine/creatinine clearance were found during periods of hypotension ...

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ژورنال

عنوان ژورنال: The American Journal of Medicine

سال: 1986

ISSN: 0002-9343

DOI: 10.1016/0002-9343(86)90302-5